1 6
30-day supply 2 capsules / day
★★★★★ 4.8 · 2,431 verified reviews

Clemence | Elegant Midi Dress with Button Closure

Clemence | Elegant Midi Dress with Button Closure

Done properly.

The clinical-study dose that supports healthy insulin response — without the fillers, blends, or guesswork the rest of the category runs on.

  • Supports healthy insulin sensitivity & glucose response
  • Helps maintain healthy cholesterol & triglyceride levels
  • Promotes steady energy and reduced sugar cravings
  • Backed by 50+ randomized controlled trials
Daily Dose
1,200mg
Form
Berberine HCl
Capsules
60 · vegetable
Fillers
None
Colour
Size
Select your offer
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In high demand — Only 38 bottles left at this price
◎
90-day guarantee
Full refund, no questions
⬡
3rd-party tested
Every batch
🚚
Free US shipping
On every order
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90-Day Bloodwork Guarantee

Run your fasting insulin or HbA1c before and after. If the numbers haven't moved in 90 days, email us — full refund, no return shipping.

Feel beautiful, move freely, and radiate confidence

Clemence midi shirt dress is more than just a dress – it’s an experience of calm elegance. It’s designed to highlight your figure and give you the freedom to move naturally. Whether you're at work or enjoying a relaxed day, confidence follows you with every step.

Why you’ll love it:

✓ Elegant fit: Designed to highlight your natural shape, giving you a light and effortless feeling all day long.

✓ Stylish details: The buttons in the front add a touch of classic charm – perfect for both everyday wear and special occasions.

✓ Versatile and timeless: The simple midi length makes it easy to style up or down, depending on the occasion.

✓ Comfort all day: The soft and breathable material makes you feel comfortable – from morning to evening.

Clemence will become a part of your wardrobe, adding a touch of grace to your everyday life.

Size Chart (Inches)

Size Bust (in) Length (in)
S 37.8 49.2
M 39.4 49.6
L 41.7 50.0
XL 44.1 50.4
2XL 46.5 50.8
3XL 48.8 51.2
View full details
As covered in
The Science

It all comes back to one hormone.

Insulin is the most powerful metabolic hormone in your body. When it works, everything works. When it stops working — quietly, gradually, often years before anyone notices — almost every system downstream of it starts to drift.

Insulin is your body's energy traffic controller. Every time you eat — especially carbs — your pancreas releases insulin to escort glucose out of the bloodstream and into your cells.

When the system runs smoothly, hormones downstream of insulin — estrogen, testosterone, cortisol, thyroid — stay in their lanes.

But cells can stop listening. This is insulin resistance — the most overlooked driver of stubborn belly fat, the 3pm energy crash, creeping cholesterol, PCOS symptoms, and the slow drift toward type 2 diabetes.

Berberine is one of the most-studied natural compounds for supporting healthy insulin response. It works through AMPK — often described as the master switch of cellular energy — to help cells respond to insulin the way they're supposed to.

01
You eat. Insulin rises.

Carbs and sugars enter the bloodstream. The pancreas releases insulin — the hormone that signals cells to absorb glucose.

02
Cells stop listening.

Over time, cells become less responsive. The pancreas releases more insulin to compensate. Glucose stays high. Damage compounds.

03
Berberine activates AMPK.

Berberine switches on AMPK — your cells' energy regulator. AMPK tells cells to absorb glucose again, even when insulin signaling is impaired.

04
The system resets.

Glucose gets used instead of stored. Insulin levels normalize. Energy stabilizes. Symptoms downstream of the broken signal begin to ease.

Insulin resistance is the master mechanism behind belly fat, energy crashes, creeping cholesterol, PCOS, and the drift toward type 2 diabetes.

Fix the signal — and the symptoms downstream begin to change.

The Evidence Base

One of the most-studied molecules in natural medicine.

Not a new compound. Not a trend. Berberine has been used in traditional medicine for over 3,000 years — and in the last two decades, modern research has caught up.

50+
Randomized controlled trials on berberine for metabolic health
Pubmed · 2003–2024
9k+
Participants studied across published trials
Aggregate meta-analysis
0.71%
Average HbA1c reduction at 1,500mg / day
27-RCT meta-analysis
3,000
Years of use in traditional medicine
Ethnobotanical record
Published Research

The studies we matched the dose to.

We didn't pick 1,500mg because it sounded impressive. We picked it because that's the dose nearly every major clinical trial used.

Meta-Analysis · 27 RCTs

Journal of Ethnopharmacology · 2015

Berberine for type 2 diabetes — efficacy comparable to first-line oral medications

Analysis of 27 randomized trials across 2,569 participants found berberine produced reductions in HbA1c, fasting blood glucose, and post-meal glucose comparable to metformin — with a favorable safety profile.

2,569
Participants
0.71%
HbA1c reduction
1,200mg
Effective dose
RCT · PCOS

European Journal of Endocrinology · 2012

Berberine vs. metformin in women with PCOS — comparable efficacy

Randomized trial in 89 women with PCOS compared berberine 1,500mg/day against metformin and placebo. Berberine matched metformin on insulin sensitivity, lipid profile, and ovulation rates.

89
Women
3 mo
Duration
≈ MET
vs. metformin
Meta-Analysis · 16 RCTs

Planta Medica · 2013

Lipid-modifying effects of berberine — LDL reductions through a statin-like mechanism

Aggregate analysis of 16 RCTs showed berberine reduced LDL by ~25 mg/dL and triglycerides by 44 mg/dL via upregulation of hepatic LDL receptors.

−25
LDL (mg/dL)
−44
TG (mg/dL)
16
RCTs pooled
Mechanism Study

Nature Medicine · 2004

Berberine activates AMPK — identification of the master metabolic mechanism

Landmark study identifying AMPK as berberine's primary molecular target. AMPK activation triggers glucose uptake, fatty acid oxidation, and energy regulation.

AMPK
Target
2004
Landmark year
3,400+
Citations since
What To Expect

This is a recalibration — not a stimulant.

Week 1–2
The settling phase

Your gut adjusts to the compound. Some people experience mild digestive shifts the first week — typically resolves by day 7. Cravings begin to soften.

✓
Week 3–4
Steadier energy

The 3pm crash eases. Energy holds through the afternoon. Sugar cravings noticeably reduced. Sleep often deepens for those whose blood sugar disrupted it.

✓
Week 6–8
Composition shifts

Subtle body composition changes — particularly around the midsection — become visible. Clothes fit differently before the scale catches up.

✓
Week 10–12
Bloodwork shifts

If you retest at this point, expect to see movement in HbA1c, fasting insulin, LDL, and triglycerides. This is the receipt.

✓
Reviewed By

Our formulas are reviewed by practicing clinicians.

Every Cleravive product is reviewed by an independent medical advisory board before it ships. Doses are matched to published trials, not to margin targets.

S
Dr. Sarah Lindsey, MD
Endocrinology · Internal Medicine

"The case for berberine isn't speculative. The mechanism is well-characterized, the trials are replicated, and at 1,500mg per day it produces measurable changes in the same metabolic markers we manage clinically."

M
Dr. Maya Chen, ND
Naturopathic Medicine · Women's Health

"In my practice I see insulin resistance driving symptoms patients have been told are 'just hormones' for years. Berberine, dosed properly, is one of the few natural compounds with clinical data robust enough to recommend."

What's Inside

The whole formula. The whole label.

Three capsules. One active ingredient. The dose the studies actually used.

What we left out — and why most brands don't
✕Magnesium stearate✕Silicon dioxide✕Microcrystalline cellulose✕Rice flour✕Titanium dioxide✕Maltodextrin✕Artificial colors✕Proprietary blends
01
Berberine HCl
Berberis aristata root extract, 97% standardized
Matches the dose used in the major clinical trials for insulin sensitivity, HbA1c reduction, PCOS, and LDL cholesterol. Split across 3 capsules to maintain steady plasma levels.
Clinical dose
1,500mg
02
Vegetable capsule
HPMC — plant cellulose
The capsule itself. No gelatin, no animal products. That's it. That's the whole formula.
Carrier
How we compare

Built differently from the ground up.

Typical Amazon berberineTypical Whole Foods berberineCleravive 001
Daily dose500–1,200mg600–1,000mg1,200mg ✓
Matches clinical study doseNoNoYes
Proprietary blendOftenOftenNone
Magnesium stearateYesYesNone
Silicon dioxide / rice flourYesOftenNone
3rd-party testedSometimesSometimesEvery batch
Customer reviews

What the 2,400+ say.

5 ★
84%
4 ★
11%
3 ★
3%
2 ★
1%
1 ★
1%
★★★★★
"My A1C went from 5.9 to 5.4 in twelve weeks."

Took three capsules a day with meals. Didn't change anything else about my diet because I wanted to know if the supplement was actually doing something. Bloodwork at the 3-month mark was the proof.

JR
Jennifer R. · Prediabetes · age 51
✓ Verified
★★★★★
"The first thing that actually moved the belly weight."

I'm 46, perimenopausal, and have been gaining weight around my middle for two years. Eight weeks on Cleravive and my waist is down an inch. Energy is steadier.

SK
Sarah K. · Perimenopause · age 46
✓ Verified
★★★★★
"LDL dropped 22 points without statins."

My cardiologist suggested a statin. I asked if I could try berberine for 90 days first. Came back to the recheck with LDL down 22 points.

MT
Marcus T. · High cholesterol · age 58
✓ Verified
Q
Why We Built This

I read thirty supplement labels. I couldn't trust any of them.

Most berberine on the market is dosed at half the clinical research level, padded with fillers nobody asked for, and hidden behind "proprietary blends."

Cleravive exists because a supplement company shouldn't optimize for the cheapest cost-per-bottle. It should optimize for whether the thing actually works — at the dose the research used.

If the studies say 1,200mg, we put 1,200mg in the bottle. If a filler doesn't earn its place, we don't add it. The label tells you the whole story. That's the entire pitch.

Sara
Founder · Cleravive
Honest Answers

The questions worth answering.

Is this "nature's Ozempic"?

No, and we won't pretend otherwise. Ozempic targets GLP-1 and produces fast appetite suppression. Berberine works on a different pathway — insulin sensitivity through AMPK — and produces modest, gradual changes over weeks and months.

How long until I feel something?

Most people notice steadier energy and reduced sugar cravings within 2–4 weeks. Body composition changes typically show up at 6–12 weeks. Bloodwork shifts usually appear at the 8–12 week recheck.

Why 1,500mg? Other brands use less.

Because that's the dose the research used. The major trials nearly all used 1,500mg/day, split into three doses. Brands using 500–1,000mg are dosing for cost, not effect.

Can I take this if I'm on metformin or a GLP-1?

Talk to your prescriber first. Berberine lowers glucose. If you're on metformin, Ozempic, Mounjaro, or any glucose-lowering medication, combining them without supervision can push glucose too low.

What if it doesn't work for me?

90-day guarantee. Finish the bottle, retest your bloodwork if relevant, see how you feel. If it didn't do what we said it would, we refund you. No questions, no return shipping.

Are there side effects?

The most common is mild GI upset in the first week as your gut adjusts. Taking capsules with food and starting with one capsule per day for the first 3 days reduces this significantly. Not recommended during pregnancy or breastfeeding.