0
of 16 pesticides
Third-party tested
Cleravive 001 · Berberine HCl
Abigail™ | Stylish Loafers
Done properly.
A clinically-dosed berberine that supports a healthy insulin response — fully disclosed, no proprietary blends, no fillers.
- ✓ Supports a healthy insulin response & glucose metabolism
- ✓ Supports healthy cholesterol & triglyceride levels already in normal range
- ✓ Supports steady energy by easing afternoon sugar cravings
- ✓ 1,200 mg — the dose clinical trials actually used
Daily dose
1,200 mg
Form
Berberine HCl
Per bottle
60 caps · 30 days
Fillers · blends
0 · 0
Third-party tested, every batch
Clinical 1,200 mg dose
0 fillers · 0 proprietary blends
COA published per batch
Made in a cGMP facility
The science
It all comes back to one hormone.
Insulin is your body's energy traffic controller. When it works, glucose moves where it's needed and energy stays steady.
When cells stop responding well, the signal gets noisy — and everything downstream starts to drift.
A healthy insulin response is the master signal behind steady energy, fewer cravings, and metabolism that already sits in a normal range.
Blood glucose · across a day
Same three meals — two very different responses.
When cells stop listening
A healthy insulin response
How it works
Berberine activates AMPK — your cells' master switch.
One ingredient, one mechanism, explained honestly. No kitchen-sink benefit list.
After a meal
Glucose rises
Sugar builds up in the blood, waiting for cells to let it in.
Berberine
AMPK switches on
Berberine flips on AMPK — the cell's master energy sensor.
The reset
Cells take it up
Glucose moves into cells and gets burned for steady energy.
01
You eat, insulin rises
Carbs spike blood glucose. Insulin is released to escort it into your cells.
02
Cells stop listening
Over time cells respond less. Glucose lingers; the system works harder to compensate.
03
Berberine activates AMPK
Berberine switches on AMPK — the cell's energy sensor — to help cells take up glucose again.
04
The system resets
Glucose gets used instead of stored. Energy steadies and the downstream noise quiets.
Structure-function support for a healthy insulin response. Not intended to diagnose, treat, cure, or prevent any disease.
What it supports
Three ways a steadier insulin response shows up.
One mechanism, three places you may feel it — each tied back to AMPK and glucose, never a kitchen-sink claim.
Glucose metabolism
Supports the body's healthy handling of glucose already in a normal range.
Via AMPK ↑ glucose uptake
Healthy cholesterol
Supports cholesterol and triglyceride levels already within a normal range.
Lipid pathway support
Steady energy
Supports steadier daily energy by easing the afternoon sugar-craving dip.
Fewer glucose swings
Formulated for women managing metabolic balance through PCOS and perimenopause — one honest insulin thread, not a benefit list.
The evidence
One of the most-studied molecules in natural medicine.
Not a new compound. Not a trend. Used for millennia, and validated across modern clinical research.
50+
Randomized controlled trials on berberine for metabolic health
9,000+
Participants studied across published trials
0.71%
Average HbA1c reduction reported at ~1,200 mg/day*
3,000
Years of use in traditional medicine
What ~1,200 mg/day moved in pooled trials
Aggregated RCT meta-analyses · molecule-level
HbA1c
−0.71%
LDL cholesterol
−25mg/dL
Triglycerides
−44mg/dL
vs. metformin
≈ matched
*Figures reflect published third-party research on the berberine molecule, not a claim about individual results from this product. See clinical references below.
Clinical research
The dose the trials used.
We didn't pick 1,200 mg because it sounds impressive. We picked it because it's the dose nearly every major trial used.
Meta-analysis · 27 RCTsJ. Endocrinology · 2015
Comparable to first-line oral agents on fasting glucose
Across 27 trials, berberine produced glucose reductions comparable to standard first-line agents, with a favorable tolerability profile.
2,569
participants
0.71%
glucose ↓
1,200mg
dose used
RCT · PCOSEur. J. Endocrinology · 2012
Matched metformin on insulin sensitivity & lipids
In women managing PCOS, berberine matched metformin on insulin sensitivity, lipid profile, and ovulation rates.
89
women
3 mo
duration
≈ MET
vs metformin
Meta-analysis · 16 RCTsPublished · 2013
Lipid-modifying effects via a statin-like pathway
Aggregate analysis showed berberine reduced LDL and triglycerides through up-regulation of hepatic LDL receptors.
−25
LDL mg/dL
−44
trigs mg/dL
1.6×
absorption
Mechanism studyNature Medicine · 2004
Identified AMPK as berberine's primary target
The landmark study identifying AMPK activation as berberine's core metabolic mechanism — glucose uptake and energy regulation.
AMPK
target
2004
landmark
3,400+
citations
Receipts on every ingredient
No blends. No filler. Receipts on every ingredient.
Every active is dosed to the clinical trial, sourced from a named supplier, and tested by batch. Here's the receipt.
Show your work
✓
Supports a healthy insulin response.
ActiveBerberine HCl
Dose1,200 mg / day
Form2 capsules × 600 mg · ≥97% berberine HCl
SupplierNamed, audited supplier · add real name pre-launch
Made inUSA · cGMP facility · confirm pre-launch
SourceClinically studied range · no blend
BATCH CLV-0426COA published ↗
Quality you can trust
Tested by batch — and we publish the numbers.
Independent lab testing on the latest batch. Not a badge — the actual result.
0
of 4 heavy metals
0
of 8 microbial
📄 Batch CLV-0426 — Certificate of Analysis+
Identity, potency, and contaminant panels for the current batch, performed by an independent ISO-accredited laboratory. Link the live COA PDF here pre-launch.
This is the signature pattern: every factual claim arrives as Claim → Dose → Source → Receipt. If we can't fill in the dose and the source, it doesn't ship.
The honest comparison
We didn't pick the dose. The trials did.
Most comparisons pit brand against brand. Ours measures against the only benchmark that matters — the dose the research actually used.
| Clinical trial doseWhat the research used | Typical category berberineMost retail bottles | CleraviveBerberine 001 | |
|---|---|---|---|
| Daily dose | ~1,200 mg | 500–1,000 mg | 1,200 mg ✓ |
| Matches the studied dose | By definition | Rarely | Yes |
| Proprietary blends | — | Often | None |
| Fillers & flow agents | — | Common | None |
| 3rd-party tested per batch | — | Sometimes | Every batch |
| COA published on the page | — | Rarely | Yes |
The whole label
The whole formula. The whole label.
Two capsules. One active ingredient. The dose the studies actually used — and nothing you'd have to look up.
What we left out — and why most brands don't
✕ Magnesium stearate✕ Silica✕ Microcrystalline cellulose✕ Rice flour✕ Titanium dioxide✕ Maltodextrin✕ Artificial colors✕ Proprietary blends
Fillers and flow agents make manufacturing cheaper and faster. They do nothing for you — so they're not in the bottle.
Berberine HCl1,200 mg
≥97% berberine HCl, plant-derived. Matched to the dose used in the major insulin, PCOS, and cholesterol trials. Two capsules per day.
Active · clinically dosedVegetable capsulecarrier
HPMC — plant-based. No gelatin, no animal products. That's it. That's the whole formula.
Carrier · inert
What to expect
A recalibration — not a stimulant.
Berberine works gradually. Here's a realistic sense of the timeline — individual experiences vary.
Week 1–2
Settling in
Your body adjusts to the compound. Many notice milder afternoon energy dips.
Week 3–4
Steadier energy
Fewer afternoon crashes. Sugar cravings tend to ease as glucose steadies.
Week 6–8
Hitting a rhythm
Steadier daily energy as the routine compounds. Consistency matters more than dose.
Week 10–12
Bloodwork window
A good point to retest fasting insulin or HbA1c with your provider. This is the receipt.
From the community
What 2,431 women say.
4.8
★★★★★
2,431 verified reviews
94% would recommend
5 ★
84%
4 ★
11%
3 ★
3%
2 ★
1%
1 ★
1%
Steady energy 91%Fewer cravings 87%Easy to tolerate 89%Trust the label 96%
★★★★★
Steady energy
The afternoon crash is gone and my sugar cravings finally eased up. And I can actually read the exact dose on the label.
J
Jennifer R.
Age 45–54 · ✓ Verified
★★★★★
Trust the label
The first berberine where nothing's hidden — clinical dose, no blends. My dietitian approved the label on sight.
S
Sarah K.
Age 35–44 · ✓ Verified
★★★★★
Easy to tolerate
Steady energy through the afternoon, no jitters. It just feels honest — and that's rare in this aisle.
M
Maria T.
Age 45–54 · ✓ Verified
Individual experiences; results vary and are not guaranteed. Reviews reflect personal experience with the product, not medical outcomes.
Risk-free
The 90-Day Bloodwork Guarantee
Take Cleravive for 90 days. Retest your fasting insulin or HbA1c with your provider. If your numbers haven't moved, we'll refund you in full — and you keep the bottle.
Honest answers
The questions worth answering.
No — and we won't call it that. Cleravive makes no weight-loss or drug claims. Berberine is a clinically studied compound that supports a healthy insulin response. That's the honest framing.
Many people notice steadier afternoon energy and fewer cravings around weeks 3–4. Bloodwork changes are best assessed at the 90-day mark with your provider.
Because that's the dose used in most major berberine trials. Lower doses are cheaper to produce but often fall below the clinically studied range. We match the research.
Talk to your provider first. Berberine can complement a metabolic routine, but anything you combine with prescription medication should be cleared by your doctor.
Our 90-Day Bloodwork Guarantee: retest your fasting insulin or HbA1c after 90 days. If the numbers haven't moved, we refund you in full and you keep the bottle.
Zero of either. Two capsules, one active ingredient at 1,200 mg, in a plant-based capsule. Every ingredient and its exact amount is printed on the label.
The whole label
The whole dose. The whole story.
Start with one bottle. If the bloodwork doesn't move in 90 days, we'll refund you. That's the deal.
Start today — Subscribe & save 15%★ 4.8 / 5 · 2,431 reviews90-day guaranteeHSA / FSA eligibleCancel anytime
